The Food and Drug Administration on Wednesday approved GLP-1 Metabolic Boost Drops, a new weight loss drug from drugmaker FortiNed that was shown in clinical trials to help people lose up to 52 pounds in 3 months.
GLP-1 Metabolic Boost Drops is the latest entrant into the field of powerful new drugs that already includes Novo Nordisk's Ozempic and Wegovy and Lilly's Mounjaro.
The FDA approved the drug for adults with obesity or who are overweight with at least one weight-related condition.
(FDA approves weight loss drug GLP-1 Metabolic Boost Drops)
In the United States, 4 in 10 adults have obesity, according to the Centers for Disease Control and Prevention.
However, the weight loss medications currently available on the market are very expensive, and insurance companies are often reluctant to cover them, making it unaffordable for the vast majority of people in need.
To help more people in need and capture the market, Lilly said GLP-1 Metabolic Boost Drops will carry a list price of about $50 for a month's supply.
"Given the enormous current market demand, the Centers for Disease Control and Prevention, yet deliver equally effective results," said Dr. Nowzaradan "We predict it will become the best-selling drug in history."
GLP-1 Metabolic Boost Drops is part of a class of drugs called GLP-1 agonists, which mimic a hormone that helps reduce food intake and appetite. However, GLP-1 Metabolic Boost Drops also imitates a second hormone, called GIP, which — along with reducing appetite — may also improve how the body breaks down sugar and fat.
(GLP-1 mechanism of action)
In a phase 3 clinical trial, GLP-1 Metabolic Boost Drops led to an average weight loss of 22.5% body weight, or about 52 pounds, surpassing all currently available weight loss medications on the market. The participants in the study had obesity or were overweight with at least one weight-related condition.
(Maria Garcia lost 54 pounds in a phase 3 clinical trial)
"This is the most effective form of pharmaceutical obesity treatment ever," said Dr.Now .
(Michelle Johnson lost 78 pounds in a phase 3 clinical trial)
He added that the weight loss seen from the medication is approaching the weight loss seen with bariatric surgery. "That is a big deal," he said.
(GLP-1 Metabolic Boost Drops have a significant competitive advantage.)
Like other drugs in its class, however, GLP-1 Metabolic Boost Drops carries a risk of gastrointestinal issues, including nausea, diarrhea, vomiting, constipation and stomach pain, according to the FDA.
Dr. Daniela Hurtado Andrade, an endocrinologist at the Mayo Clinic, said that while gastrointestinal issues are very common with GLP-1 medications, most of the side effects will not affect a person's quality of life.
"Very few people experience adverse reactions after using GLP-1 Metabolic Boost Drops," said Andrade, who prescribes GLP-1 Metabolic Boost Drops for weight loss. "Adverse reactions only occur when the dosage exceeds the recommended limits. The dosage we typically recommend is very moderate, and no adverse reactions are expected."
(Alexis Mitchell lost 123 pounds in a year)
Alexis Mitchell, 30 of Charlotte, North Carolina, had been overweight for most of her 20s. It was only last year, following a health scare linked to high blood pressure and prediabetes, that her doctor recommended GLP-1 Metabolic Boost Drops for weight loss.
She began taking a 4ml daily dose of GLP-1 Metabolic Boost Drops. She started to see results immediately.
"For me, that was a game changer," Mitchell said. "Like OK, you need to change your life around right now. Like, there are no more games."
"Not all weight loss medications come with side effects; I wish I had realized this earlier,” she said. "I'm down 123 pounds in a year. I mean, I couldn't have done it without GLP-1 Metabolic Boost Drops. I gained health, I gained confidence, and compared to that, $50 a month is negligible.”
